Comparison of expression levels of the twenty-six genes that changed expression in spinal cord 24 h following transection at both P7 and P28.

<p>All but two of these genes (Timp1 and Stxbp2) were in the immune/inflammatory category. The magnitude of the expression changes was generally similar at the two ages, but more genes (six: IL1β, MARCO, novel-2, CSF2RB, IL1-R1, novel-4) showed greater upregulation at P7 than at P28 (three: novel-1, novel-6, novel-7). A search of Ensembl, NCBI “Gene” and GO categories showed that all of these novel genes are involved in immune/inflammatory functions (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0099080#pone.0099080.s001" target="_blank">Tables S1</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0099080#pone.0099080.s002" target="_blank">S2</a>).