Bland-Altman plot of the optimal parameter configuration (z = 4, Th<i>_C</i> = 13) for the RRate application, determined by data from Phase I and II (n = 300).

<p>The mean difference (bias) is −0.13 breaths/min and the standard deviation (SD) is 1.98 breaths/min. The number of observations is displayed as marker intensity. The dashed lines represent the 95<i>^th</i> percentile range. The vertical lines correspond to the limits for fast breathing by age <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0099266#pone.0099266-World1" target="_blank">[1]</a>.