<p>The schematic diagram of tissue distribution of Compound 1 in Wistar rats after 180/kg of orally administered Compound 1 (mean ± S.D., n = 6).</p
<p>Plasma pharmacokinetic data following administration of compound 22 (i.v. dose of 5 mg/kg and p.o...
<p>Histological micrographs of hematoxylin-eosin stained skin section (H&E×100) showing normal subcu...
1<p>polyphenol compounds (1500 nmol) were applied in perfusion experiments of 60 min, respectively.<...
<p>The plasma concentration-time profiles of Compound 1 after oral administration at 45, 180 and 720...
<p>The plasma concentration-time profiles of Compound 1 after intravenous administration at 180 mg/k...
<p>t<sub>1/2</sub>, half-life; Ke: elimination rate constant; Tmax: time of peak concentration; Cmax...
<p>Plasma, skin, and intestine samples were collected from the mice orally administered 30 mg/kg Com...
<p>The table lists all compounds that were repeatedly administered to male Wistar rats for a time sp...
<p>2A Plasma concentration-time profile of BBR after oral administration of 200 mg/kg in 48 h (n = 6...
<p>Schematic representation of the rat brain regions analyzed for the receptor expression at the lev...
<p><b>A</b>: Rats fed RD and treated by gavage daily for twenty-eight consecutive days with vehicle ...
<p>(a) Summary scatter plot. Positions along axes report the median binding affinity of all compound...
The size of the square represents the weight. CI, confidence interval; k, number of cohort-level com...
<p>Each symbol represents an individual rat. Circles = females; Diamonds = males; Green = control di...
<p>Area under the curve for circulating metabolites as a percentage of fosmetpantotenate (parent) af...
<p>Plasma pharmacokinetic data following administration of compound 22 (i.v. dose of 5 mg/kg and p.o...
<p>Histological micrographs of hematoxylin-eosin stained skin section (H&E×100) showing normal subcu...
1<p>polyphenol compounds (1500 nmol) were applied in perfusion experiments of 60 min, respectively.<...
<p>The plasma concentration-time profiles of Compound 1 after oral administration at 45, 180 and 720...
<p>The plasma concentration-time profiles of Compound 1 after intravenous administration at 180 mg/k...
<p>t<sub>1/2</sub>, half-life; Ke: elimination rate constant; Tmax: time of peak concentration; Cmax...
<p>Plasma, skin, and intestine samples were collected from the mice orally administered 30 mg/kg Com...
<p>The table lists all compounds that were repeatedly administered to male Wistar rats for a time sp...
<p>2A Plasma concentration-time profile of BBR after oral administration of 200 mg/kg in 48 h (n = 6...
<p>Schematic representation of the rat brain regions analyzed for the receptor expression at the lev...
<p><b>A</b>: Rats fed RD and treated by gavage daily for twenty-eight consecutive days with vehicle ...
<p>(a) Summary scatter plot. Positions along axes report the median binding affinity of all compound...
The size of the square represents the weight. CI, confidence interval; k, number of cohort-level com...
<p>Each symbol represents an individual rat. Circles = females; Diamonds = males; Green = control di...
<p>Area under the curve for circulating metabolites as a percentage of fosmetpantotenate (parent) af...
<p>Plasma pharmacokinetic data following administration of compound 22 (i.v. dose of 5 mg/kg and p.o...
<p>Histological micrographs of hematoxylin-eosin stained skin section (H&E×100) showing normal subcu...
1<p>polyphenol compounds (1500 nmol) were applied in perfusion experiments of 60 min, respectively.<...