<p>D<sub>3</sub> rescued G1/G0 arrest in R38+, and to a lesser degree in R38-, when added in the lineage-commitment stage. (A) 48 h G1/G0 arrest after sequential treatment with two inducing agents during the precommitment and lineage-commitment phases (RA/RA, RA/D<sub>3</sub>, RA/-, D<sub>3</sub>/D<sub>3</sub>, D<sub>3</sub>/RA, and D<sub>3</sub>/-). (B) 72 h G1/G0 arrest (continuation of treatment with a second inducing agent). Untreated control gates were set to 45% G1/G0, 35% S and 20% G2/M. For clarity, p-values are not indicated above bars due to the existence of multivariate comparison between cell lines, treatments, and time. However, p-values of interest are mentioned specifically in the main text.</p
<p>(A) Flow cytometry of indicated Ramos transductants, showing cell number relative to DNA content ...
<p> <b>h treatment with 5-floururacil, cytosine arabinoside, doxorubicin and cisplatin.</b> SKW-3 ce...
<p>(A–B) Histograms depict the quantification of RAD-51 foci in (A) control and (B) <i>lab-1(RNAi)</...
<p>D<sub>3</sub> increases the early differentiation marker CD38 in RA-resistant HL-60 cell lines. (...
<p>Oxidative metabolism (respiratory burst) at 72 h after sequential treatment with two inducing age...
<p>D<sub>3</sub> increases the differentiation marker CD11b in RA-resistant HL-60 cell lines. (A) 48...
<p>D<sub>3</sub> induced monocytic differentiation marker CD14 expression in wild-type (WT) and both...
<p>Individual Western blots of whole cell lysates are representative of at least three repeats. GAPD...
<p>Control WT cells are round; RA-treated R38+ and R38− also retain a round, stem-like appearance. W...
<p><b>A</b>. AML14.3D10 cells were incubated in the presence of rhSP-D (10µg/ml) (Right panel) or in...
<p>The percentage of subs G1, G1, S, and G2/M populations were analysed using flow cytometry from pr...
<p>HGC-27 cells were treated for 48 h with RAD001 (10 nM) and/or MK-2206 (100 nM), cell cycle was an...
<p>(<b>A</b>–<b>D</b>) BJ hTERT cells were plated and shifted to various first blocking conditions f...
<p>(<b>A</b>) After 2 Gy RT, average RAD51 foci number increased significantly at 24 and 72 h in bot...
<p>(A) Synchronized HeLa cells were treated with 0–20 µM DhL for 72 h and subjected to DNA flow cyto...
<p>(A) Flow cytometry of indicated Ramos transductants, showing cell number relative to DNA content ...
<p> <b>h treatment with 5-floururacil, cytosine arabinoside, doxorubicin and cisplatin.</b> SKW-3 ce...
<p>(A–B) Histograms depict the quantification of RAD-51 foci in (A) control and (B) <i>lab-1(RNAi)</...
<p>D<sub>3</sub> increases the early differentiation marker CD38 in RA-resistant HL-60 cell lines. (...
<p>Oxidative metabolism (respiratory burst) at 72 h after sequential treatment with two inducing age...
<p>D<sub>3</sub> increases the differentiation marker CD11b in RA-resistant HL-60 cell lines. (A) 48...
<p>D<sub>3</sub> induced monocytic differentiation marker CD14 expression in wild-type (WT) and both...
<p>Individual Western blots of whole cell lysates are representative of at least three repeats. GAPD...
<p>Control WT cells are round; RA-treated R38+ and R38− also retain a round, stem-like appearance. W...
<p><b>A</b>. AML14.3D10 cells were incubated in the presence of rhSP-D (10µg/ml) (Right panel) or in...
<p>The percentage of subs G1, G1, S, and G2/M populations were analysed using flow cytometry from pr...
<p>HGC-27 cells were treated for 48 h with RAD001 (10 nM) and/or MK-2206 (100 nM), cell cycle was an...
<p>(<b>A</b>–<b>D</b>) BJ hTERT cells were plated and shifted to various first blocking conditions f...
<p>(<b>A</b>) After 2 Gy RT, average RAD51 foci number increased significantly at 24 and 72 h in bot...
<p>(A) Synchronized HeLa cells were treated with 0–20 µM DhL for 72 h and subjected to DNA flow cyto...
<p>(A) Flow cytometry of indicated Ramos transductants, showing cell number relative to DNA content ...
<p> <b>h treatment with 5-floururacil, cytosine arabinoside, doxorubicin and cisplatin.</b> SKW-3 ce...
<p>(A–B) Histograms depict the quantification of RAD-51 foci in (A) control and (B) <i>lab-1(RNAi)</...