Effects of chronic drug treatments on social activity on a new territory.

<p>Two or three animals on the same treatment were observed for 10(simultaneously-initiated) contacts. The contacts were shorter (<b>A</b>) but more frequent (<b>B</b>) among the control <i>Gria1−/−</i> mice than among the WT mice. Chronic valproate, but not lithium, moderated the activity of the <i>Gria1−/−</i> mice to the level found in the WT mice. Data are means ± SEM (n = 6–15). *<i>p</i><0.05, ***<i>p</i><0.001 for the differences between genotypes after the same treatment; ^#<i>p</i><0.05 for the differences from the control within the same genotype (two-way ANOVA followed by Bonferroni <i>post-hoc</i> test).