<p>A) Cavalieri estimates of total hippocampal volume in <i>Bmal1</i> (+/+), (+/−), and (−/−) mice at approximately 100 days of age. Estimates were calculated from the cresyl violet stained tissue series utilized in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0099527#pone-0099527-g003" target="_blank">Figure 3</a> for pyknotic cell counts. Hippocampal volume estimates were not significantly different across genotypes.</p
<p>(A) Weights of rTg9191 mice (APP/TTA), littermates harboring only the activator gene (TTA), only ...
Even in the absence of neurodegenerative diseases, progressing age often coincides with cognitive de...
Even in the absence of neurodegenerative diseases, progressing age often coincides with cognitive de...
<p>Representative images (A) and morphometric analysis (B) of hippocampus in Nissl-stained sagittal ...
<p>(A) No cell loss was detected in the CA3 region of the hippocampus of hAPP-J20 mice at 6, 24 and ...
<p>All plots use box-and-whiskers diagrams. The box indicates data that lie within the 25th and 75th...
We recently mapped two quantitative trait loci that have widespread effects on hippocampal architect...
<p>(<b>a</b>) Schematic of adult mouse brain regions examined. Volumes of the whole brain (<b>b</b>)...
<p>A) Photomicrograph of cresyl violet stained pyknotic cells, shown by the white arrows. Scale bar ...
Our current understanding of litter variability in neurodevelopmental studies using mice may limit t...
<p>Total levels of DNA (A) and RNA (B) extracted from the hippocampus at different developmental age...
<p>A: Representative <sup>1</sup>H MR spectra acquired from the hippocampus of a 12-month-old wild-t...
<p>Significantly fewer BrdU-positive (A, <i>n</i> = 8 HD and <i>n</i> = 9 WT animals), DCX-positive ...
Hippocampal atrophy is increasingly described in many neurodegenerative syndromes in humans, includi...
<p>*Significant differences compared to WT animals, #significant differences compared to HET mice. W...
<p>(A) Weights of rTg9191 mice (APP/TTA), littermates harboring only the activator gene (TTA), only ...
Even in the absence of neurodegenerative diseases, progressing age often coincides with cognitive de...
Even in the absence of neurodegenerative diseases, progressing age often coincides with cognitive de...
<p>Representative images (A) and morphometric analysis (B) of hippocampus in Nissl-stained sagittal ...
<p>(A) No cell loss was detected in the CA3 region of the hippocampus of hAPP-J20 mice at 6, 24 and ...
<p>All plots use box-and-whiskers diagrams. The box indicates data that lie within the 25th and 75th...
We recently mapped two quantitative trait loci that have widespread effects on hippocampal architect...
<p>(<b>a</b>) Schematic of adult mouse brain regions examined. Volumes of the whole brain (<b>b</b>)...
<p>A) Photomicrograph of cresyl violet stained pyknotic cells, shown by the white arrows. Scale bar ...
Our current understanding of litter variability in neurodevelopmental studies using mice may limit t...
<p>Total levels of DNA (A) and RNA (B) extracted from the hippocampus at different developmental age...
<p>A: Representative <sup>1</sup>H MR spectra acquired from the hippocampus of a 12-month-old wild-t...
<p>Significantly fewer BrdU-positive (A, <i>n</i> = 8 HD and <i>n</i> = 9 WT animals), DCX-positive ...
Hippocampal atrophy is increasingly described in many neurodegenerative syndromes in humans, includi...
<p>*Significant differences compared to WT animals, #significant differences compared to HET mice. W...
<p>(A) Weights of rTg9191 mice (APP/TTA), littermates harboring only the activator gene (TTA), only ...
Even in the absence of neurodegenerative diseases, progressing age often coincides with cognitive de...
Even in the absence of neurodegenerative diseases, progressing age often coincides with cognitive de...