<p>Histogram in panel A summarizes the effects of acetylcholine (ACh) and isoproterenol (Iso) on AP parameters. Representative examples of the AP response to both agonists are shown in B. Panel C summarizes changes in beat-to-beat CL variability on a subgroup of n = 8 cells which underwent both treatments sequentially.</p
The sphingosine-1-phosphate receptor modulator fingolimod (FTY720) elicits a negative chronotropic e...
Previous studies in our laboratory have demonstrated that the acute sympathomimetic effects of isopr...
<p>Results are expressed as increase in basal rate (beats min<sup>-1</sup>). When the preparation wa...
Panel [A] shows representative spontaneous electrogram recordings from healthy (left), IsP (middle) ...
<p>Isoprenaline (Iso) was applied as an adrenergic agonist on hiPSC-CMs (A) and hESC-CMs (B) and ind...
<p>Frequency (top) and dissipation (bottom) time curves obtained with a spontaneously beating hPS-CM...
<p>A–B: Each histogram shows a PSTH (trials, 10; bin width, 10 ms) of visual responses of two neuron...
<p>A, Multielectrode array (MEA) tracing of dose dependent effects isoproterenol (1–1000 nM) on beat...
<p>(Top) The histogram summarizes changes induced on AP parameters by ivabradine (red) and ryanodine...
<p>Panel A: a steady AP waveform from a spontaneously beating single SANC is shown in red (trace 1)....
<p><b>Panel A</b>: Experimental data on AC activity (in pmol/mg/min) in mouse hearts and ventricular...
<p>*P<0.05 when compared with either glucagon or isoproterenol alone</p><p>Chronotropic E<sub>max</s...
<p>Cell Index (CI) data generated by Xcelligence RTCA when serum starved HL-1 cells were treated wit...
[A-C] Representative contractions (LAmplitude) from healthy [A], IsP [B] and AuP [C] iPSC-CM in the ...
The sphingosine-1-phosphate receptor modulator fingolimod (FTY720) elicits a negative chronotropic e...
The sphingosine-1-phosphate receptor modulator fingolimod (FTY720) elicits a negative chronotropic e...
Previous studies in our laboratory have demonstrated that the acute sympathomimetic effects of isopr...
<p>Results are expressed as increase in basal rate (beats min<sup>-1</sup>). When the preparation wa...
Panel [A] shows representative spontaneous electrogram recordings from healthy (left), IsP (middle) ...
<p>Isoprenaline (Iso) was applied as an adrenergic agonist on hiPSC-CMs (A) and hESC-CMs (B) and ind...
<p>Frequency (top) and dissipation (bottom) time curves obtained with a spontaneously beating hPS-CM...
<p>A–B: Each histogram shows a PSTH (trials, 10; bin width, 10 ms) of visual responses of two neuron...
<p>A, Multielectrode array (MEA) tracing of dose dependent effects isoproterenol (1–1000 nM) on beat...
<p>(Top) The histogram summarizes changes induced on AP parameters by ivabradine (red) and ryanodine...
<p>Panel A: a steady AP waveform from a spontaneously beating single SANC is shown in red (trace 1)....
<p><b>Panel A</b>: Experimental data on AC activity (in pmol/mg/min) in mouse hearts and ventricular...
<p>*P<0.05 when compared with either glucagon or isoproterenol alone</p><p>Chronotropic E<sub>max</s...
<p>Cell Index (CI) data generated by Xcelligence RTCA when serum starved HL-1 cells were treated wit...
[A-C] Representative contractions (LAmplitude) from healthy [A], IsP [B] and AuP [C] iPSC-CM in the ...
The sphingosine-1-phosphate receptor modulator fingolimod (FTY720) elicits a negative chronotropic e...
The sphingosine-1-phosphate receptor modulator fingolimod (FTY720) elicits a negative chronotropic e...
Previous studies in our laboratory have demonstrated that the acute sympathomimetic effects of isopr...
<p>Results are expressed as increase in basal rate (beats min<sup>-1</sup>). When the preparation wa...
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