Morphology of adult worms after RNAi of SmJNK <i>in vitro</i> and subsequent transfer of parasites into mice.

<p>Adult 37-day-old worms were fixed and stained, and visualized by confocal microscopy as described in the text. A, B and C show normal worms treated with GFP dsRNA, whereas D, E and F show morphological changes in worms treated with SmJNK dsRNA. A and B - the tubercules (TB) are highlighted on the tegument; C – female worm ovary (OV) showing immature and mature oocytes; D – muscular structure of a worm without tubercules; E- subtegumentar lesion (SL); F- immature ovary.