Cytokines production by iNKT cells from dengue infected patients with and without stimulation with α-GalCer.

<p>Each dot represents percentage of interferon gamma (IFN-γ)⁺ (a–b) and IL-4⁺ (e–f) iNKT cells from DF (a,e) and DHF (b,f) at day 0 and month 6, with (stimulated) and without (unstimulated) α-GalCer stimulation. At day 0 (c, g, i) and 6 months (d, h, j), percentage of IFN-γ⁺ iNKT cells (c,d), IL-4⁺ iNKT cells (g, h) and IFN-γ/IL-4 ratio (i, j) upon α-GalCer stimulation, comparing cells from healthy, OFI, DF and DHF groups. Mann-Whitney test, were used for statistical comparison, p<0.05 was considered as statistically significant difference (*p<0.05, **p<0.01, ***p<0.001).