Baicalin protects against UVB irradiation-induced amplification of MMP-1 expression.

<p>(A) Skin specimens of dorsal trunk were harvested for immuno-staining using primary antibodies of MMP-1. Images are representative of results from 5 tissue samples. Original magnification ×40. (B) Total RNA was extracted from biopsied skin samples of different groups. MMP-1 mRNA was determined by real-time RT-PCR analysis. Results are shown as means±SD (n = 5). The symbol (#) indicates a significant difference (p<0.05) between the control group and the UVB-irradiated group. Asterisks (*) indicate significant differences of p<0.05, respectively, between the baicalin-treated and non-treated groups of irradiated mice.