Putative pathway for scutellarin and chlorogenic acids biosynthesis in <i>E. breviscapus</i>.

<p>The major products previously found in <i>E. breviscapus</i> are surrounded by shaded boxes. Enzymes found in this study are boxed; new putative enzyme (flavone 6-hydroase, F6H) was surrounded by dashed line box. Enzymes involved in the pathways are: 4CL, 4-coumarate: CoA ligase; C3H, <i>p</i>-coumarate 3-hydroxylase; C4H, cinnamate 4-hydroxylase; CHI, chalcone isomerase; CHS, chalcone synthase, DFR, dihydroflavonol 4-reductase; F3′5′H flavonoid 3′5′ hydroxylase; F3′H, flavonoid 3′ hydroxylase; F3H, flavanone 3-hydroxylase = flavonol synthase (FLS); FSII, flavone synthase II; HCGQT, hydroxycinnamoyl D-glucose: quinate hydroxycinnamoyl transferase; HCT, hydroxycinnamoyl CoA shikimate/quinate hydroxycinnamoyl transferase; HQT, hydroxycinnamoyl CoA quinate hydroxycinnamoyl transferase; LDOX, leucoanthocyanidin dioxygenase = anthocyanidin synthase (ANS); OMT, <i>O</i>-methyltransferase; PAL, phenylalanine ammonia lyase; RT, rhamnosyl transferase; UFGT, UDPG-flavonoid glucosyl transferase; UGCT, UDP glucose: cinnamate glucosyl transferase; F7GAT, flavonoid 7-O-glucuronosyltransferase.