Complete XY gonadal sex reversal in <i>Fgfr2^hob/hob</i> embryos on B6.

<p>A–C) Immunostaining with anti-AMH antibody of gonadal sections from XY wild-type (A), XX wild-type (B) and XY <i>Fgfr2^hob/hob</i> (C) embryos at 12.5 dpc. D–F) anti-FOXL2 immunostaining of samples equivalent to those in A–C. G–I) WMISH for <i>Insl3</i> (a marker of Leydig cells) of gonads with same genotypes as A–C. J–M) <i>Oct4</i> WMISH of 11.5 dpc (17 ts) gonads from control XY (J), XX (K), XY <i>Fgfr2^hob/hob</i> and XX <i>Fgfr2^hob/hob</i> gonads. N–Q) <i>Oct4</i> WMISH of 13.5 dpc gonads from embryos of the same genotype as J-M.