<p>* Half of the cortex and the striatal tissues collected from each animal were used for real time qPCR analysis.</p><p>The other half striatum and cortex were used in the aggregation assay. The number in brackets indicates the sample size used for in the aggregation assay when it was different from the one used in qPCR studies.HOM; zQ175 HOM mice, HET: zQ175 HET.</p
Quantification of human mHTT (A) or HTT aggregates (B and C). Analysis of striatal tissues from untr...
<p>Metabolite values with an LC Model fit of a Cramér-Rao lower bound (CRLB) above 20% were excluded...
<p>(<b>A</b>) Representative amplification plot of qPCR for the transcripts encoding the total of mM...
<p>* Half of the cortex and the striatal tissues collected from each animal were used for real time ...
<p>* Half of the cortex and the striatal tissues collected from each animal were used for real time ...
<p>* Half of the cortex and the striatal tissues collected from each animal were used for real time ...
Whole brain lysates of an age series of R6/2 (left), hetQ175 (middle), and BACHD (right) mice were a...
<p>The numbers at the bottom of each figure indicate the megabases. Pink color lines on the top indi...
<p>A. Aggregate load in cortical tissues from 12-week-old R6/2×TG2 KO mice. The background readings ...
<p>A. Aggregate load in cortical tissues from 12-week-old R6/2×TG2 KO mice. The background readings ...
Whole brain homogenates from (A) a 12 week-old R6/2 (500 μL at 3 mg/mL) and (B) a 14 month-old hetQ1...
<p>(<b>A</b>) Using an automated microscope, whole mouse brain sections were scanned by high resolut...
<p>A) Longitudinal analysis of 16S rRNA gene copies per ng of stool DNA. The groups of mice tested a...
<p>(A) The SEPRION ligand based ELISA assay was used to quantify HTT aggregation in the cortex, hipp...
<p>(<b>A</b>) Representative images depicting MAB2174-ir in the cortex and striatum of wild type and...
Quantification of human mHTT (A) or HTT aggregates (B and C). Analysis of striatal tissues from untr...
<p>Metabolite values with an LC Model fit of a Cramér-Rao lower bound (CRLB) above 20% were excluded...
<p>(<b>A</b>) Representative amplification plot of qPCR for the transcripts encoding the total of mM...
<p>* Half of the cortex and the striatal tissues collected from each animal were used for real time ...
<p>* Half of the cortex and the striatal tissues collected from each animal were used for real time ...
<p>* Half of the cortex and the striatal tissues collected from each animal were used for real time ...
Whole brain lysates of an age series of R6/2 (left), hetQ175 (middle), and BACHD (right) mice were a...
<p>The numbers at the bottom of each figure indicate the megabases. Pink color lines on the top indi...
<p>A. Aggregate load in cortical tissues from 12-week-old R6/2×TG2 KO mice. The background readings ...
<p>A. Aggregate load in cortical tissues from 12-week-old R6/2×TG2 KO mice. The background readings ...
Whole brain homogenates from (A) a 12 week-old R6/2 (500 μL at 3 mg/mL) and (B) a 14 month-old hetQ1...
<p>(<b>A</b>) Using an automated microscope, whole mouse brain sections were scanned by high resolut...
<p>A) Longitudinal analysis of 16S rRNA gene copies per ng of stool DNA. The groups of mice tested a...
<p>(A) The SEPRION ligand based ELISA assay was used to quantify HTT aggregation in the cortex, hipp...
<p>(<b>A</b>) Representative images depicting MAB2174-ir in the cortex and striatum of wild type and...
Quantification of human mHTT (A) or HTT aggregates (B and C). Analysis of striatal tissues from untr...
<p>Metabolite values with an LC Model fit of a Cramér-Rao lower bound (CRLB) above 20% were excluded...
<p>(<b>A</b>) Representative amplification plot of qPCR for the transcripts encoding the total of mM...