Altered methylation of cell adhesion genes is associated with changes in mRNA expression.

<p>Changes in methylation status in term and preterm preeclamptic placentas resulted in altered mRNA expression of (<b>A</b>) Cadherin 11 (CDH11), (<b>B</b>) Collagen, type V, alpha 1 (COL5A1), (<b>C</b>) Neuronal Cell Adhesion Molecule 1 (NCAM1) and (<b>D</b>) Tissue Necrosis Factor (TNF). Each dot represents a placental sample from each enrolled study patient. Solid bars represent mean of each group. *p<0.05.