<p>The x and y axes show the values of the constants by which the elements of the main and epistatic effects, respectively, are multiplied in the hierarchical fitness landscape. The plot shows the logarithm (base 10) of the ratio of mean fitness of the recombining to that of the non-recombining populations at generation 100, averaged across 100 simulations. Parameters take values: and .</p
Following transmission, HIV-1 adapts in the new host by acquiring mutations that allow it to escape ...
Fitness interactions between mutations, referred to as epistasis, can strongly impact evolution. For...
Accepted Article first published online November 2009.The mutational landscape model of adaptive seq...
Recombination has the potential to facilitate adaptation. In spite of the substantial body of theory...
<div><p>Recombination has the potential to facilitate adaptation. In spite of the substantial body o...
Recombination has the potential to facilitate adaptation. In spite of the substantial body of theory...
Recombination has the potential to facilitate adaptation. In spite of the substantial body of theory...
Although fitness landscapes are central to evolutionary theory, so far no biologically realistic exa...
Recombination has the potential to facilitate adaptation. In spite of the substantial body of theory...
<p>We screened a total of 150 randomly sampled fitness topographies with 3, 5 and 7 LFGs. <i>T<sub>f...
<p>A) no baseline epistasis (), B) positive baseline epistasis (), C) negative baseline epistasis ()...
<p>Each point in the above plots represents one fitness topography and its position is given by <i>T...
Following transmission, HIV-1 adapts in the new host by acquiring mutations that allow it to escape ...
Fitness interactions between mutations, referred to as epistasis, can strongly impact evolution. For...
Following transmission, HIV-1 adapts in the new host by acquiring mutations that allow it to escape ...
Following transmission, HIV-1 adapts in the new host by acquiring mutations that allow it to escape ...
Fitness interactions between mutations, referred to as epistasis, can strongly impact evolution. For...
Accepted Article first published online November 2009.The mutational landscape model of adaptive seq...
Recombination has the potential to facilitate adaptation. In spite of the substantial body of theory...
<div><p>Recombination has the potential to facilitate adaptation. In spite of the substantial body o...
Recombination has the potential to facilitate adaptation. In spite of the substantial body of theory...
Recombination has the potential to facilitate adaptation. In spite of the substantial body of theory...
Although fitness landscapes are central to evolutionary theory, so far no biologically realistic exa...
Recombination has the potential to facilitate adaptation. In spite of the substantial body of theory...
<p>We screened a total of 150 randomly sampled fitness topographies with 3, 5 and 7 LFGs. <i>T<sub>f...
<p>A) no baseline epistasis (), B) positive baseline epistasis (), C) negative baseline epistasis ()...
<p>Each point in the above plots represents one fitness topography and its position is given by <i>T...
Following transmission, HIV-1 adapts in the new host by acquiring mutations that allow it to escape ...
Fitness interactions between mutations, referred to as epistasis, can strongly impact evolution. For...
Following transmission, HIV-1 adapts in the new host by acquiring mutations that allow it to escape ...
Following transmission, HIV-1 adapts in the new host by acquiring mutations that allow it to escape ...
Fitness interactions between mutations, referred to as epistasis, can strongly impact evolution. For...
Accepted Article first published online November 2009.The mutational landscape model of adaptive seq...