Percent nucleotide identity of genes encoding the V regions of FtGroEL mAbs to the most homologous germline genes.

<p>**No D gene was identified by the IGBLAST program (<a href="http://www.ncbi.nlm.nih.gov/igblast/" target="_blank">http://www.ncbi.nlm.nih.gov/igblast/</a>) using the minimum requirement of five contiguous nucleotides. Shared IGHV, IGHD or IGKV genes are shown in the same color.</p><p>a, Antigen extracts of LVS adjuvanted with TiterMax®Gold and CpG ODN 1826 i.p., s.c., i.d. twice, followed by same antigen adjuvanted with CpG ODN 1826 i.p. and i.n., followed by 2×10³ and 2×10⁴ LVS i.n.</p><p>b, Antigen extracts of the OAg-deficient LVS mutant WbtI adjuvanted with TiterMax®Gold and CpG ODN 1826 i.p., followed by 2×10⁵ or 2×10⁷ LVS i.d., then the same antigen extracts of WbtI i.p.</p><p>c, 1.6×10⁵–2.3×10⁷ LVS i.d., followed by antigen extracts of LVS i.p.</p><p>d, 1.6×10⁵ or 2.3×10⁶ LVS i.d., followed by antigen extracts of WbtI i.p.</p><p>e, 3×10⁵ LVS i.d., 2×10⁵ LVS i.d., 2×10⁶ LVS i.p.</p><p>f, 2×10⁴ LVS i.n., followed by FtLPS mAb Ab3 i.p., then 4×10⁵ LVS i.n.