<p>A Representative islets showing hematoxylin and eosin staining of islets from C57BL/6, GLP-1RKO and GIPRKO mice. B –Insulitis severity score (% of total number of islets analysed and graded according to level of lymphocyte infiltration). Values are mean ± SEM of 6 observations. *p<0.05 compared to respective treatment of C57BL/6 mice.</p
<p>A Representative islets showing insulin (red) and glucagon (green) immunoreactivity from C57BL/6,...
<p>Cohorts of 15 w old mice were treated either with paquinimod (Paq; 1 mg/kg/day) or vehicle (Ctrl)...
<p><b>A.</b> Representative images of the islets from each treatment group. β-cells are visualised b...
<p><b>A.</b> Paraffin sections of female mice of the indicated ages were stained with Hoechst 33342....
<p>Islets obtained from animals injected with MAb 8E6G4 IgG (50 and 100 µg), control IgG, and PBS we...
<p>The severity of islet inflammation was quantified by the degree of insulitis. Islets were categor...
<p>Paraffin sections of pancreatic islets collected from mice one week after completion of the STZ t...
<p>Thin sections of pancreatic tissue from 120<sup>+/+</sup> and TLR4<sup>−/−</sup> mice were staine...
<p><b>A.</b> Representative photomicrographs of distinct patterns observed in pancreas sections. His...
<p>(A) Cumulative diabetes incidence in male and female GF and CONV-R mice. (B) Representative image...
<p>MLDS treated BALB/c mice received FTY720, sunitinib, or anti-VEGFR3 mAb starting from the first S...
A longitudinal study of lymphocytic infiltration in the endocrine pancreas of non-obese diabetic mic...
<p>(A) Insulitis was assessed by histological examination at 13 weeks of age before clinical onset o...
<p>Mice were treated with Ad-m IL-10/Ad-m IGF-1. Pancreata were collected at 3 weeks after treatment...
<p>Islets from db/+, db/db, and MIN6 cells left untreated or treated with the indicated LPS concentr...
<p>A Representative islets showing insulin (red) and glucagon (green) immunoreactivity from C57BL/6,...
<p>Cohorts of 15 w old mice were treated either with paquinimod (Paq; 1 mg/kg/day) or vehicle (Ctrl)...
<p><b>A.</b> Representative images of the islets from each treatment group. β-cells are visualised b...
<p><b>A.</b> Paraffin sections of female mice of the indicated ages were stained with Hoechst 33342....
<p>Islets obtained from animals injected with MAb 8E6G4 IgG (50 and 100 µg), control IgG, and PBS we...
<p>The severity of islet inflammation was quantified by the degree of insulitis. Islets were categor...
<p>Paraffin sections of pancreatic islets collected from mice one week after completion of the STZ t...
<p>Thin sections of pancreatic tissue from 120<sup>+/+</sup> and TLR4<sup>−/−</sup> mice were staine...
<p><b>A.</b> Representative photomicrographs of distinct patterns observed in pancreas sections. His...
<p>(A) Cumulative diabetes incidence in male and female GF and CONV-R mice. (B) Representative image...
<p>MLDS treated BALB/c mice received FTY720, sunitinib, or anti-VEGFR3 mAb starting from the first S...
A longitudinal study of lymphocytic infiltration in the endocrine pancreas of non-obese diabetic mic...
<p>(A) Insulitis was assessed by histological examination at 13 weeks of age before clinical onset o...
<p>Mice were treated with Ad-m IL-10/Ad-m IGF-1. Pancreata were collected at 3 weeks after treatment...
<p>Islets from db/+, db/db, and MIN6 cells left untreated or treated with the indicated LPS concentr...
<p>A Representative islets showing insulin (red) and glucagon (green) immunoreactivity from C57BL/6,...
<p>Cohorts of 15 w old mice were treated either with paquinimod (Paq; 1 mg/kg/day) or vehicle (Ctrl)...
<p><b>A.</b> Representative images of the islets from each treatment group. β-cells are visualised b...