Aberrant electromyographic characteristics in <i>Sod1</i>^−/− muscle imply deficits in neurotransmission and denervation.

<p>(<i>A</i>) Representative traces of gastrocnemius compound muscle action potential (CMAP) when stimulated at 0.2 Hz and 10 Hz. Dashed line shows the amplitude of the initial peak. Traces were arbitrarily spaced 1ms apart for easy visualization. (<i>B</i>) Quantitative result of CMAP decrement in WT (N = 17, 7 months old, white) and <i>Sod1</i>^−/− (N = 11, 7 months old, gray) mice in response to repetitive nerve stimulation. Data are plotted as mean with error bars representing standard error. All mice are between 4 to 10 months of age. Statistics: <i>t-test</i>, *p<0.05, **p<0.01.