<p>(<i>A</i>) Scatter plot showing the relationship between AChRs total area and its occupancy by axon shown as % of overlap over the AChRs total area in wild-type (WT, white) and <i>Sod1</i><sup>−/−</sup> (gray) mice. NMJs labeled as “#” and “1, 2 and 3” are examples of individual NMJs in WT and <i>Sod1</i><sup>−/−</sup> mice which were recorded for electrophysiology shown in (<i>C</i>). (<i>B</i>) Quantification of average AChR density (<i>F<sub>int</sub>/Area</i>) in EDL muscle NMJs from WT (n = 30, white) and <i>Sod1</i><sup>−/−</sup> (n = 30, gray) mice. Data are plotted as mean with error bars representing standard error. (<i>C</i>) Representative images of individual EDL NMJs showing the overlap (yellow) between axonal (green) and AC...
BACKGROUND: The neuromuscular junction (NMJ) is a specialised synapse formed between a lower motor n...
The mammalian neuromuscular junction (NMJ) is a useful model synapse to study the relationship betwe...
We monitored presynaptic exocytosis and vesicle recycling at neuromuscular junctions of transgenic m...
<p>(<i>A</i>, <i>top</i>) Representative traces of spontaneous mEPPs in wild-type (WT) and <i>Sod1</...
<p>NMJs in EDL and gastrocnemius muscles were visualized via Thy1-YFP fluorescence in the presynapti...
<p>A) Illustrates raw recordings of 5 EPPs from adult WT mice and the two groups of symptomatic SOD1...
The neuromuscular junction (NMJ) is the large, cholinergic relay synapse through which mammalian mot...
<p><b>A.</b> Representative pictures of P7 NMJs in WT (left) and mutant (right) triangularis sterni ...
<p>A and B– Representative images of nerve terminal profile from VAChT WT and VAChT KD<sup>HOM</sup>...
<p>A) Schematic diagram showing location of muscles which were innervated by either vulnerable or re...
<p>A and B – Representative images of two NMJs from diaphragm muscle of VAChT WT and VAChT KD<sup>HO...
The balanced action of both pre− and postsynaptic organizers regulates the formation of neuromuscula...
<p>A and B – Representative images of nerve terminal profile from VAChT WT and VAChT KD<sup>HOM</sup...
The neuromuscular junction (NMJ) is the ultimate synapse in the somatic motor system, allowing skele...
<p>(<b>A</b>). Denervated junctions were fragmented and dispersed without terminal axons. Remodeled ...
BACKGROUND: The neuromuscular junction (NMJ) is a specialised synapse formed between a lower motor n...
The mammalian neuromuscular junction (NMJ) is a useful model synapse to study the relationship betwe...
We monitored presynaptic exocytosis and vesicle recycling at neuromuscular junctions of transgenic m...
<p>(<i>A</i>, <i>top</i>) Representative traces of spontaneous mEPPs in wild-type (WT) and <i>Sod1</...
<p>NMJs in EDL and gastrocnemius muscles were visualized via Thy1-YFP fluorescence in the presynapti...
<p>A) Illustrates raw recordings of 5 EPPs from adult WT mice and the two groups of symptomatic SOD1...
The neuromuscular junction (NMJ) is the large, cholinergic relay synapse through which mammalian mot...
<p><b>A.</b> Representative pictures of P7 NMJs in WT (left) and mutant (right) triangularis sterni ...
<p>A and B– Representative images of nerve terminal profile from VAChT WT and VAChT KD<sup>HOM</sup>...
<p>A) Schematic diagram showing location of muscles which were innervated by either vulnerable or re...
<p>A and B – Representative images of two NMJs from diaphragm muscle of VAChT WT and VAChT KD<sup>HO...
The balanced action of both pre− and postsynaptic organizers regulates the formation of neuromuscula...
<p>A and B – Representative images of nerve terminal profile from VAChT WT and VAChT KD<sup>HOM</sup...
The neuromuscular junction (NMJ) is the ultimate synapse in the somatic motor system, allowing skele...
<p>(<b>A</b>). Denervated junctions were fragmented and dispersed without terminal axons. Remodeled ...
BACKGROUND: The neuromuscular junction (NMJ) is a specialised synapse formed between a lower motor n...
The mammalian neuromuscular junction (NMJ) is a useful model synapse to study the relationship betwe...
We monitored presynaptic exocytosis and vesicle recycling at neuromuscular junctions of transgenic m...