SATB1 regulates gene expression in CRC cells.
- Yi Zhang (9093)
- Xiuyun Tian (185166)
- Hong Ji (293468)
- Xiaoya Guan (413577)
- Wei Xu (28953)
- Bin Dong (147019)
- Min Zhao (66793)
- Meng Wei (124295)
- Chunxiang Ye (590012)
- Yuan Sun (15554)
- Xiaosun Yuan (590013)
- Chen Yang (207381)
- Chunyi Hao (413578)
Publication date
June 2014
DOIAbstract
<p>The expression level of genes associated with CRC carcinogenesis and metastasis were determined in empty vector, SATB1-shRNA1, and pcDNA3.1-SATB1 cell lines by RT-PCR. Knockdown of SATB1 expression downregulated S100A4, VEGF-B, MMP-9, TGFβ1, and CTGF expression and upregulated CTNNB1 and CDH1 expression. SATB1 overexpression resulted in the opposite effect.</p
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