<p>Knockdown of YAP expression by siRNA reduced clonogenic survival in HEC-1-B cells, resulting in an increase in radiation sensitivity with a dose enhancement factor at 10% survival (DEF 0.1) of 1.36. Results are shown in means ±standard deviations (bars) in triplicate experiments. Similar trends were obtained in other three independent experiments.</p
Radiation therapy (RT) is a standard treatment for solid tumors and about 50% of patients with cance...
<p><b>A–I</b>) <b>Target knockdown affects survival of IR exposed cells.</b> HCT116 cells transfecte...
It has long been accepted that the radiation-induced heri-table effects in mammalian cells are the r...
<p>(A) The level of Dicer expression, cleavage of PARP and processing of caspase-3 and -9 in U1810 c...
Aim: To determine whether the number of non-rejoining G2-chromatid breaks can predict the radiosensi...
<p>A. HUVEC cell number plotted against time after siRNA transfection. Untransfected and RISC-free s...
The clonogenic ability (reproductive cell death) of Chinese hamster V79 cells was measured after tre...
<p>(<b>A</b>) BRCA2 protein expression following knockdown was assessed by western blot. (<b>B</b>) ...
Purpose: To address the relationship between the bystander effect and the adaptive response that can...
An adaptive response may be defined as the effect of a small priming dose of radiation modifying the...
The aim of this study was to investigate effects of high LET α-radiation in combination with inhibit...
<p>a) Clonogenic assay performed in DU-145 after treatment with different doses of VPA for 48 h befo...
A lot of efforts have focused on the RNA interference(RNAi) using small interfering RNAs(siRNAs) as ...
Radioadaptive response (RAR) describes phenomena where small conditioning doses of ionizing radiatio...
<p><i>A, B,</i> HT-29 (A) or DLD1 (B) cells were transfected with <i>Beclin 1</i> vs control siRNA a...
Radiation therapy (RT) is a standard treatment for solid tumors and about 50% of patients with cance...
<p><b>A–I</b>) <b>Target knockdown affects survival of IR exposed cells.</b> HCT116 cells transfecte...
It has long been accepted that the radiation-induced heri-table effects in mammalian cells are the r...
<p>(A) The level of Dicer expression, cleavage of PARP and processing of caspase-3 and -9 in U1810 c...
Aim: To determine whether the number of non-rejoining G2-chromatid breaks can predict the radiosensi...
<p>A. HUVEC cell number plotted against time after siRNA transfection. Untransfected and RISC-free s...
The clonogenic ability (reproductive cell death) of Chinese hamster V79 cells was measured after tre...
<p>(<b>A</b>) BRCA2 protein expression following knockdown was assessed by western blot. (<b>B</b>) ...
Purpose: To address the relationship between the bystander effect and the adaptive response that can...
An adaptive response may be defined as the effect of a small priming dose of radiation modifying the...
The aim of this study was to investigate effects of high LET α-radiation in combination with inhibit...
<p>a) Clonogenic assay performed in DU-145 after treatment with different doses of VPA for 48 h befo...
A lot of efforts have focused on the RNA interference(RNAi) using small interfering RNAs(siRNAs) as ...
Radioadaptive response (RAR) describes phenomena where small conditioning doses of ionizing radiatio...
<p><i>A, B,</i> HT-29 (A) or DLD1 (B) cells were transfected with <i>Beclin 1</i> vs control siRNA a...
Radiation therapy (RT) is a standard treatment for solid tumors and about 50% of patients with cance...
<p><b>A–I</b>) <b>Target knockdown affects survival of IR exposed cells.</b> HCT116 cells transfecte...
It has long been accepted that the radiation-induced heri-table effects in mammalian cells are the r...