<p>A. Plasma levels of eHSPA12B in septic mice. eHSPA12B was elevated at 6(n = 6 for each time points of the 2 groups). * <i>p</i><0.001, compared with sham group; † <i>p</i><0.001, compared with the level at 6h. Data analyses with Student’s <i>t</i>-test. B. Plasma level of eHSPA12B in mice with sepsis of different severity. CLP-1, mice with once puncture in the cecum; CLP-2, mice with twice punctures in the cecum. * <i>p</i><0.001, compared with sham group; † <i>p</i><0.001, compared with CLP-1 group. Data analyses with ANOVA test. C. Relationship between the levels of eHSPA12B and IL-6 (<i>p</i><0.001). Data analyses with Pearson’s correlation analysis.</p
<p>Serum concentrations of (A) TNF-α, (B) IL-1β, (C) IL-6, and (D) IFN-γ at 6 hours after bacterial ...
Serum was collected 3, 10, 15 and 30 days post-infection for analysis of soluble factor levels. The ...
<p>Concentration of IFNγ (<b>a</b>), TNFα (<b>b</b>), IL-10 (<b>c</b>), IL-1β (<b>d</b>) and IL-6 (<...
<p>(<b>A</b>) tumor necrosis factor-α (TNF-α), (<b>B</b>) interleukin-6 (IL-6), (<b>C</b>) IL-10 and...
<p>Blood samples were taken at the indicated time points. <b>A.</b> TNF-á levels in sera from WT and...
<p>Balb/C mice were subjected to lethal sepsis by CLP, and intraperitoneally administered with contr...
Endothelium-derived molecules may be predictive to organ injury. Heat shock protein (HSP) A12B is ma...
<p>The test compounds were administered 2 h prior to the induction of sepsis by LPS (100 mg/kg bw, i...
Objective Clinical sepsis-associated biomarkers were utilized in a cecal ligation and puncture (CLP)...
Background: Growth Arrest-Specific Gene 6 product (Gas6) is, like anticoagulant protein C, a vitamin...
<p>Levels of the TNF-α and IL-6 protein in the kidney were determined by Western blotting (A)(C) and...
<p>N = 7/group. The differences in S100A6 levels were not confirmed (A, p = 0.45 in the ANOVA). Howe...
<p>Mices were subjected to CLP surgery. Renal tissue sections were collected from the CLP group at v...
<p>Animals were infected i.v. with 5x10<sup>6</sup> GAS AP1. (<b>A</b>-<b>I</b>) Nine BALB/c and 10 ...
International audienceMortality due to sepsis remains unacceptably high, especially for septic shock...
<p>Serum concentrations of (A) TNF-α, (B) IL-1β, (C) IL-6, and (D) IFN-γ at 6 hours after bacterial ...
Serum was collected 3, 10, 15 and 30 days post-infection for analysis of soluble factor levels. The ...
<p>Concentration of IFNγ (<b>a</b>), TNFα (<b>b</b>), IL-10 (<b>c</b>), IL-1β (<b>d</b>) and IL-6 (<...
<p>(<b>A</b>) tumor necrosis factor-α (TNF-α), (<b>B</b>) interleukin-6 (IL-6), (<b>C</b>) IL-10 and...
<p>Blood samples were taken at the indicated time points. <b>A.</b> TNF-á levels in sera from WT and...
<p>Balb/C mice were subjected to lethal sepsis by CLP, and intraperitoneally administered with contr...
Endothelium-derived molecules may be predictive to organ injury. Heat shock protein (HSP) A12B is ma...
<p>The test compounds were administered 2 h prior to the induction of sepsis by LPS (100 mg/kg bw, i...
Objective Clinical sepsis-associated biomarkers were utilized in a cecal ligation and puncture (CLP)...
Background: Growth Arrest-Specific Gene 6 product (Gas6) is, like anticoagulant protein C, a vitamin...
<p>Levels of the TNF-α and IL-6 protein in the kidney were determined by Western blotting (A)(C) and...
<p>N = 7/group. The differences in S100A6 levels were not confirmed (A, p = 0.45 in the ANOVA). Howe...
<p>Mices were subjected to CLP surgery. Renal tissue sections were collected from the CLP group at v...
<p>Animals were infected i.v. with 5x10<sup>6</sup> GAS AP1. (<b>A</b>-<b>I</b>) Nine BALB/c and 10 ...
International audienceMortality due to sepsis remains unacceptably high, especially for septic shock...
<p>Serum concentrations of (A) TNF-α, (B) IL-1β, (C) IL-6, and (D) IFN-γ at 6 hours after bacterial ...
Serum was collected 3, 10, 15 and 30 days post-infection for analysis of soluble factor levels. The ...
<p>Concentration of IFNγ (<b>a</b>), TNFα (<b>b</b>), IL-10 (<b>c</b>), IL-1β (<b>d</b>) and IL-6 (<...