Triptolide induces cytotoxicity in HepG2 cells.

<p>(A) HepG2 cells were treated with triptolide at various concentrations for 6, 12 and 24 h. Cell viability was determined by an MTT assay. The viability of the cells without triptolide treatment is defined as 100%. (B) HepG2 cells were treated with triptolide at various concentrations for 24 h. LDH leakage was measured. The data are represented as the mean ± SD from three independent experiments. <i>*P</i><0.05, <i>**P</i><0.01 versus vehicle control (0.1% DMSO).