Recovery of the fecal microbiota over time in piperacillin/tazobactam treated animals.

<p>Mice received subcutaneous piperacillin/tazobactam (n = 4) or normal saline (n = 4) for 3 days. Quantitative real-time PCR was used to measure fecal bacterial DNA in fecal specimens collected either before treatment or 1, 7 or 14 days following treatment. The y-axis shows the quantity of amplified DNA detected per 1 ng of template DNA. Red circles, mean values for clindamycin-treated mice. Black squares, mean values for control mice. * <i>p</i><0.05. Symbols indicate differences between the experimental and control groups for individual time points. Error bars represent standard error.