Follow-up of homing and maturation markers on pDCs in blood and lymph nodes following SIVagm infection.

<p>PDCs were defined as shown in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004241#ppat.1004241.s001" target="_blank">Figure S1</a>. Expression levels of the chemokine receptors (A, B) CXCR3 and (C, D) CCR7 and the (E, F) co-stimulatory CD86 on (A, C, E) blood and (B, D, F) LN pDCs are shown as MFI after substraction of isotype-control values (n = 6 AGMs). The expression levels of (G) HLA-DR and (H) CD40 were analyzed on another group of 8 AGMs. PDCs were here defined as CD20⁻ BDCA2⁺ CD123⁺ HLA-DR⁺. Data are presented as medians and interquartile ranges. Day zero represents the median of all the time points before infection. See legend to <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004241#ppat-1004241-g002" target="_blank">Figure 2</a> for a description of p-values (logarithm transformation for panel B).