The dendritic spine alteration of pyramidal neurons in the hippocampus of P14 and P21 rats after chronic lead exposure.

<p>A) Golgi-Cox impregnated dendritic arborization and dendritic spines in four groups: control (Ctrl) P14, lead (Pb) P14, Ctrl P21, lead (Pb) P21. Scale bar = 10 µm; B) Representative sections (20 µm) of Golgi-Cox stained dendrites of pyramidal neurons in hippocampus in four groups; C) Histograms plot showing the alteration of dendritic spine density (spines/10 µm) after lead exposure in P14 and P21 rats. (***p<0.001).