Proposed molecular targets in TQ anti-cancer efficacy in SASVO3 cells.

<p>TQ induced cell death in SASVO3 cells via two distinct antineoplastic activities that can induce apoptosis and autophagy. TQ induced autophagosome accumulation, resulting in autophagic cell death and increased DNA damage, potential Δ<i>Ψ</i>m collapse, chromosome condensation, and caspase-9 activation-dependent apoptosis.