<p>Growth curves of viruses recovered from the full length constructs containing the mutations displayed by pCH2, pCH3 and pCH83 (VpCH2, VpCH3 and VpCH83, respectively) in comparison to the virus recovered from the wt infectious cDNA clone. The curves show the results of a representative experiment in titer (TCID<sub>50</sub>) at a given time point (hours post infection – hpi). The infection was done at an m.o.i. of 0.0003.</p
<p>(A) Construction of influenza B NP mutants by systematically deleting the N-terminal coding regio...
(A). The amino-acid sequence of the 6K region from WT SINV, Δ6K SINV, p7 SINV, M2 SINV, and Vpu SINV...
<p>Different concentrations of (WT and mutant) virus were added to C8166 cell cultures. Three to fou...
<p>In the upper part, the cDNA sequence of part of the TURBS region is shown for the constructs spec...
<p>The gene segment composition of the each reassortant is given next to each chart: Hk68 genes (bla...
<p>One-step growth curves of the recombinant viruses, rA/P1-FMDV and rO/CHA/99, and the epidemic vir...
<div><p>(A) MDCK cells were inoculated at an MOI of 0.1 and 0.001, and virus growth of WH and WH N66...
<p>The gene segment constellation of each reassortant is given next to each chart: Hk68 genes (black...
<p>A) Multi-step growth kinetics of wt vRB-1B, vP6.1mut and vP6.1rev were performed in triplicates a...
<p>HFF cells were infected at an MOI of 0.5 PFU/cell. (A and B) Total virus at various d p.i. Cells ...
<p>Growth curves of viruses in PK-15 cells were measured using RT-qPCR assays (viral RNA copies/ml) ...
(A) TMZR5 cells were pre-stimulated with different doses of IFNα14 for 24 hours prior to infection w...
<p>Viral yield in time for the A/Brisbane/59/2007 (H1N1) WT (filled circles) and H275Y mutant (open ...
Calu-3 cells were infected with 0.01 MOI of SARS-CoV-2 virus B.6, B.1.617.1 (Kappa), and B.1.617.2 (...
<p>A: Virus growth curves as determined by TCID<sub>50</sub> endpoint dilution assays. HzAM1 cells w...
<p>(A) Construction of influenza B NP mutants by systematically deleting the N-terminal coding regio...
(A). The amino-acid sequence of the 6K region from WT SINV, Δ6K SINV, p7 SINV, M2 SINV, and Vpu SINV...
<p>Different concentrations of (WT and mutant) virus were added to C8166 cell cultures. Three to fou...
<p>In the upper part, the cDNA sequence of part of the TURBS region is shown for the constructs spec...
<p>The gene segment composition of the each reassortant is given next to each chart: Hk68 genes (bla...
<p>One-step growth curves of the recombinant viruses, rA/P1-FMDV and rO/CHA/99, and the epidemic vir...
<div><p>(A) MDCK cells were inoculated at an MOI of 0.1 and 0.001, and virus growth of WH and WH N66...
<p>The gene segment constellation of each reassortant is given next to each chart: Hk68 genes (black...
<p>A) Multi-step growth kinetics of wt vRB-1B, vP6.1mut and vP6.1rev were performed in triplicates a...
<p>HFF cells were infected at an MOI of 0.5 PFU/cell. (A and B) Total virus at various d p.i. Cells ...
<p>Growth curves of viruses in PK-15 cells were measured using RT-qPCR assays (viral RNA copies/ml) ...
(A) TMZR5 cells were pre-stimulated with different doses of IFNα14 for 24 hours prior to infection w...
<p>Viral yield in time for the A/Brisbane/59/2007 (H1N1) WT (filled circles) and H275Y mutant (open ...
Calu-3 cells were infected with 0.01 MOI of SARS-CoV-2 virus B.6, B.1.617.1 (Kappa), and B.1.617.2 (...
<p>A: Virus growth curves as determined by TCID<sub>50</sub> endpoint dilution assays. HzAM1 cells w...
<p>(A) Construction of influenza B NP mutants by systematically deleting the N-terminal coding regio...
(A). The amino-acid sequence of the 6K region from WT SINV, Δ6K SINV, p7 SINV, M2 SINV, and Vpu SINV...
<p>Different concentrations of (WT and mutant) virus were added to C8166 cell cultures. Three to fou...