<p>Computerized calculation of γH2AX foci in the nuclei of cells. Statistical significance refers to comparison with control cells (Fig. 6b).</p
(A) Representative immunofluorescence images of 387 GSCs harvested at 30 min, 24 hrs and 48 hours af...
<p>Correlation between HP1α and H2AXγ signals was determined by eye from overlaid immunofluorescence...
<p><b>A</b>, Appearance of 53BP1-positive foci (red) in heterochromatin (accumulated blue) and euchr...
<p>(A) FANCD2 immunostaining of synchronised HeLa cells in S-, G2- and M-phase. (B) FANCD2 nuclear f...
One half hour after irradiation cells were fixed and immunostained for γH2AX foci formation. Immunof...
<p>A, B, HCT116+3+5 cells with control or <i>MSH3</i> shRNA were irradiated (2 Gy) and then probed w...
An approach based on track-structure calculations has been developed to take account of artefacts oc...
<p>This allows the study of the distribution of foci in the whole volume of irradiated endothelial c...
<p>(A) Quantification of foci per cell from the analysis of a minimum of 1000 DM1 fibroblast nuclei ...
When early radiation damage to biological systems is studied based on the formation of foci at the l...
<p>(A) Representative images of γH2AX foci in untreated cells, and in cells irradiated with 2 Gy 1h,...
`These authors contributed equally. Key words: confocal microscopy, image quantification, nucleus, p...
<p>(A) Multiple nuclear γ-H2AX foci (green) are clearly discernible in a lymphocyte of a healthy con...
<p>(A–B) Histograms depict the quantification of RAD-51 foci in (A) control and (B) <i>lab-1(RNAi)</...
<p>(A) The number of γ-H2AX foci per cell nucleus (N>13) was manually quantified for each time point...
(A) Representative immunofluorescence images of 387 GSCs harvested at 30 min, 24 hrs and 48 hours af...
<p>Correlation between HP1α and H2AXγ signals was determined by eye from overlaid immunofluorescence...
<p><b>A</b>, Appearance of 53BP1-positive foci (red) in heterochromatin (accumulated blue) and euchr...
<p>(A) FANCD2 immunostaining of synchronised HeLa cells in S-, G2- and M-phase. (B) FANCD2 nuclear f...
One half hour after irradiation cells were fixed and immunostained for γH2AX foci formation. Immunof...
<p>A, B, HCT116+3+5 cells with control or <i>MSH3</i> shRNA were irradiated (2 Gy) and then probed w...
An approach based on track-structure calculations has been developed to take account of artefacts oc...
<p>This allows the study of the distribution of foci in the whole volume of irradiated endothelial c...
<p>(A) Quantification of foci per cell from the analysis of a minimum of 1000 DM1 fibroblast nuclei ...
When early radiation damage to biological systems is studied based on the formation of foci at the l...
<p>(A) Representative images of γH2AX foci in untreated cells, and in cells irradiated with 2 Gy 1h,...
`These authors contributed equally. Key words: confocal microscopy, image quantification, nucleus, p...
<p>(A) Multiple nuclear γ-H2AX foci (green) are clearly discernible in a lymphocyte of a healthy con...
<p>(A–B) Histograms depict the quantification of RAD-51 foci in (A) control and (B) <i>lab-1(RNAi)</...
<p>(A) The number of γ-H2AX foci per cell nucleus (N>13) was manually quantified for each time point...
(A) Representative immunofluorescence images of 387 GSCs harvested at 30 min, 24 hrs and 48 hours af...
<p>Correlation between HP1α and H2AXγ signals was determined by eye from overlaid immunofluorescence...
<p><b>A</b>, Appearance of 53BP1-positive foci (red) in heterochromatin (accumulated blue) and euchr...