Immunohistochemical analysis of CD11c⁺ DCs in lymph node, spleen, and tumor tissues.

<p>(A) Tissue sections of the lymph nodes, spleen, and tumors from mice that received polyplex micelles with the indicated transgenes were immunostained with an anti-CD11c antibody. Scale Bar = 200 µm. (B) The number of CD11c⁺ DCs was significantly increased in the lymphatic organs of GM-CSF and SART3/CD40L+GM-CSF transfection groups. In tumor tissues, a significant increase of CD11c⁺ DC numbers was detected in SART3/CD40L+GM-CSF vaccine group. <i>*P<</i>0.05, <i>**P<</i>0.01 vs. mock control (n = 5).