Validation of ZFP36 target genes inferred from MIC analysis of microarray gene expression data.

<p>Gene set enrichment analysis <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0102625#pone.0102625-Subramanian1" target="_blank">[20]</a> profiles are shown for 10016 genes, rank-ordered by MIC score. Normalised Kolmogorov-Smirnov enrichment scores (NES) and false discovery rate q values (FDR) are shown. (A) using a gene set (n = 237) representing mRNAs that are significantly up-regulated in <i>Tis11/ZFP36</i>-knock-out mouse fibroblasts <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0102625#pone.0102625-Ishmael1" target="_blank">[21]</a>, (B) using a gene set (n = 152) representing mRNAs that display a significantly decreased rate of degradation in <i>Tis11/ZFP36</i>-deficient mouse fibroblasts <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0102625#pone.0102625-Lai1" target="_blank">[22]</a>.