MAP2K4 increases HSP27 and MMP-2 expression <i>in vivo</i>.

<p><b>A</b>) MMP transcript expression of tumor samples. The levels of MMP-2, MMP-9, MMP-10 and MMP-13 transcript levels were measured by qRT/PCR, normalized to GAPDH, and expressed as the mean ± SEM percentage of VC. Each tumor sample was run twice, in duplicates of N = 2, and compared to a reference sample. <b>B-F</b>) Quantification of phospho- and total protein expression in tumor samples. Protein expression was measured by Western Blot, twice for each tumor, compared to a reference sample, and graphed data are the mean ± SEM percent of VC. * denotes p≤0.05 between the indicated groups.