Targeted mutagenesis of intron 2 of the <i>taf6</i> gene.

<p>(A) Mutations of intron motifs are indicated with arrows in the TAF6 minigene constructs. HeLa cell transfection and splice product analysis was carried out as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0102399#pone-0102399-g003" target="_blank">Figure 3</a>. The percentage of exogenous TAF6δ mRNA is graphically shown (x-axis). (B) As in panel A except mutations were focused on poly G motifs found within intron 2. (P<0.05 = *; P<0.01 = **; P<0.001 = ***).