<p>Autophagy was mophologically characterized by transmission electron microscopy (A). Splenic tissues were harvested at 24h after CLP. In sham mice (a and b), splenocytes were normal in appearance with proper mitochondria distribution. Sham mice revealed autophagic vacuoles (arrowheads) in the cytosol with double- or single-membrane structures containing digested cytoplasmic components. CLP mice (c and d) displayed less autophagic vacuolization. A representative cell showed apoptosis in CLP mice with cell shrinkage, nuclear condensation and cellular disorganization (d, arrow). Quantification of autophagic vacuoles in sham and CLP mice (B). The number of autophagic vacuoles was counted under the microscope at 7,500× from 30 non-repeating mi...
<p>Induction of autophagic vacuoles, with double membranes characteristic of autophagosomes, was det...
<p>(A) TEM micrograph: the “N” represents nucleus and the arrows indicate autophagosomes. Numerous a...
<p>Immunofluorescent microscopy (20X) of renal cortex harvested at 48 hours after LPS in young mice ...
<p>(A) Representative high magnification electron micrographs showing autophagic vacuoles in detruso...
<p>Electron microscope sections obtained from CA1 regions of 15-month-old 3xTg-AD mice. Sections sho...
<p>(A) Electron micrographs of hepatocytes in the livers of control and L-<i>G6pc</i>-/- mice. Arrow...
<p>After oral M90T infection, crypt (A-C) and villous epithelial cells (E-G) in the terminal ileum r...
In autophagy, a portion of cytoplasm is first segregated into a membrane-bound vacuole which then ac...
<p>(A) Transmission electron microscopy (8000x) micrograph. The arrows indicated autophagosomes and ...
<p><b>A–B.</b>) Clenbuterol increases autophagosomal marker LC3-II in the liver of mice treated for ...
Stereological principles were applied to the morphometric analysis of the autophagic process induced...
<p>Electron microscopy images of autophagic vacuoles in control, 10 μM or 20 μM PI-103-treated or 6 ...
<p><b>A</b>, upper panels, presence of vesicles with cytoplasmic content (some marked by arrows) 12 ...
<p>(<b>A</b>) Representative transmission electron microscopic images of autophagosomes in the proxi...
<p>Pancreas sections from <i>Lepr<sup>flox/flox</sup></i> (A) and <i>Lepr<sup>flox/flox</sup> RIP-Cr...
<p>Induction of autophagic vacuoles, with double membranes characteristic of autophagosomes, was det...
<p>(A) TEM micrograph: the “N” represents nucleus and the arrows indicate autophagosomes. Numerous a...
<p>Immunofluorescent microscopy (20X) of renal cortex harvested at 48 hours after LPS in young mice ...
<p>(A) Representative high magnification electron micrographs showing autophagic vacuoles in detruso...
<p>Electron microscope sections obtained from CA1 regions of 15-month-old 3xTg-AD mice. Sections sho...
<p>(A) Electron micrographs of hepatocytes in the livers of control and L-<i>G6pc</i>-/- mice. Arrow...
<p>After oral M90T infection, crypt (A-C) and villous epithelial cells (E-G) in the terminal ileum r...
In autophagy, a portion of cytoplasm is first segregated into a membrane-bound vacuole which then ac...
<p>(A) Transmission electron microscopy (8000x) micrograph. The arrows indicated autophagosomes and ...
<p><b>A–B.</b>) Clenbuterol increases autophagosomal marker LC3-II in the liver of mice treated for ...
Stereological principles were applied to the morphometric analysis of the autophagic process induced...
<p>Electron microscopy images of autophagic vacuoles in control, 10 μM or 20 μM PI-103-treated or 6 ...
<p><b>A</b>, upper panels, presence of vesicles with cytoplasmic content (some marked by arrows) 12 ...
<p>(<b>A</b>) Representative transmission electron microscopic images of autophagosomes in the proxi...
<p>Pancreas sections from <i>Lepr<sup>flox/flox</sup></i> (A) and <i>Lepr<sup>flox/flox</sup> RIP-Cr...
<p>Induction of autophagic vacuoles, with double membranes characteristic of autophagosomes, was det...
<p>(A) TEM micrograph: the “N” represents nucleus and the arrows indicate autophagosomes. Numerous a...
<p>Immunofluorescent microscopy (20X) of renal cortex harvested at 48 hours after LPS in young mice ...