Effect of <i>H. pylori</i> on gene expression change during ulcer healing.

<p>Gastric ulcer was induced by topical serosal application of acetic acid. A single gavage of 10⁶ <i>H. pylori</i> was performed 2 days after ulcer induction. Ulcerated or non-ulcerated area were harvested 1, 7 or 30 Days after <i>H. pylori</i> inoculation. H,K-ATPase (A), and TFF2 (B) mRNA was detected by real-time PCR. Data are shown as fold change normalized to non-ulcerated region of uninfected group (ulcer −, <i>H. pylori −</i>). mean ± SEM. *, p<0.05 vs. intact region. ^#, p<0.05 vs. no <i>H. pylori</i> inoculation group.