<p>The proportion of stochastic variability in the Hurdle Model explained by cell cycle is shown on the primary y-axis (left) for <i>ranked</i> and <i>unranked</i> genes, with box giving the 25<sup>th</sup>, 50<sup>th</sup> and 75<sup>th</sup> percentiles, and whiskers showing 1.5 times the inter-quartile range. The deflated scale on the secondary y-axis (right) shows the deviance as a percentage of the most completely explained gene (TOP2A, 27%) and is intended as an upper bound for the amount of remaining biological deviance in non-cell-cycle genes. Under this conservative rescaling, cell cycle explains only 25% of the deviance in 75% of unranked genes.</p
<p>The <i>x</i>-axis shows bins of <i>p-</i>values of the significance of cell cycle regulation. Fro...
International audienceThe cell cycle is the fundamental process of cell populations, it is regulated...
International audienceThe cell cycle is the fundamental process of cell populations, it is regulated...
<p>(A) Hurdle model strength of evidence of cell cycle phase dependent expression for genes within o...
<p>Graphs were plotted for CV value thresholds t = 0.5 t = 0.1, t = 0.05 and t = 0.01. Percentage of...
<p>Boxes range from the 25<sup>th</sup> to the 75<sup>th</sup> percentiles, solid lines within boxes...
Expression of many genes varies as a cell transitions through different cell-cycle stages. How coupl...
<p>Box-plot graph of Ct value shows the median values as lines across the box. Lower and upper boxes...
Expression of many genes varies as a cell transitions through different cell-cycle stages. How coupl...
Expression of many genes varies as a cell transitions through different cell-cycle stages. How coupl...
<p>Box-plot graph of Ct value shows the median value as a line across the box. Lower and upper boxes...
<p>Six parameters were calculated for five gene groups: phase specific cell-cycle genes at <i>G1 (70...
<p>Box-plot graph of Ct value shows the median values as lines across the box. Lower and upper boxes...
International audienceThe cell cycle is the fundamental process of cell populations, it is regulated...
International audienceThe cell cycle is the fundamental process of cell populations, it is regulated...
<p>The <i>x</i>-axis shows bins of <i>p-</i>values of the significance of cell cycle regulation. Fro...
International audienceThe cell cycle is the fundamental process of cell populations, it is regulated...
International audienceThe cell cycle is the fundamental process of cell populations, it is regulated...
<p>(A) Hurdle model strength of evidence of cell cycle phase dependent expression for genes within o...
<p>Graphs were plotted for CV value thresholds t = 0.5 t = 0.1, t = 0.05 and t = 0.01. Percentage of...
<p>Boxes range from the 25<sup>th</sup> to the 75<sup>th</sup> percentiles, solid lines within boxes...
Expression of many genes varies as a cell transitions through different cell-cycle stages. How coupl...
<p>Box-plot graph of Ct value shows the median values as lines across the box. Lower and upper boxes...
Expression of many genes varies as a cell transitions through different cell-cycle stages. How coupl...
Expression of many genes varies as a cell transitions through different cell-cycle stages. How coupl...
<p>Box-plot graph of Ct value shows the median value as a line across the box. Lower and upper boxes...
<p>Six parameters were calculated for five gene groups: phase specific cell-cycle genes at <i>G1 (70...
<p>Box-plot graph of Ct value shows the median values as lines across the box. Lower and upper boxes...
International audienceThe cell cycle is the fundamental process of cell populations, it is regulated...
International audienceThe cell cycle is the fundamental process of cell populations, it is regulated...
<p>The <i>x</i>-axis shows bins of <i>p-</i>values of the significance of cell cycle regulation. Fro...
International audienceThe cell cycle is the fundamental process of cell populations, it is regulated...
International audienceThe cell cycle is the fundamental process of cell populations, it is regulated...