Acetylcholine receptor alpha peptide binding to survivin positive cells in myasthenics by five color FACS analysis.
- Linda L. Kusner (599569)
- Michael J. Ciesielski (602287)
- Alexander Marx (343033)
- Henry J. Kaminski (599568)
- Robert A. Fenstermaker (602288)
Publication date
July 2014
DOIAbstract
<p>A) FITC labeled AChR-alpha subunit peptide binding to total myasthenic PBMC (0.44%), B) Excess unlabeled AChR-alpha subunit peptide followed by competitive binding of FITC-AChR peptide (0.03%). C) Control PBMC, subject number 19, (SVN+/CD38+/CD138+/CD20+ gated sub-population) showing FITC-AChR-alpha subunit peptide binding (0.33% of gated cells). D–F; Myasthenic patient PBMC (SVN+/CD38+/CD138+/CD20+ gated sub-population) showing FITC-AChR-alpha subunit peptide binding (1.55% (pt#10), 6.54% (pt#15) and 2.50% (pt#14) of total gated cells; <i>n</i> = 3).</p
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