<p>(<b>a</b>) snapshot of YS domain (the YS domain is growing over time as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0102718#pone-0102718-g007" target="_blank">figure 7</a>). Morphogen concentration is denoted as z-axis height. Substrate has relatively low values inside the growing rectangle, and relatively high outside the growing rectangle. Y equals to 1.0 inside the rectangle and equal to 0.0 outside that rectangle. The initial rectangular is 5 space steps wide by 10 space steps long. The length of the rectangular increases one space step every 10,000 time steps. Space step dx = 0.3, time step dt = 0.4dx<sup>2</sup>. (<b>b, c</b>) profile of S along the dotted line as shown in panel a. The high/low value of...
<p>F-actin protrusions produced by the two Leading Cells (LCs) on one side during epidermal cell mig...
Actin-based cell motility and force generation are central to immune response, tissue development, a...
<p>The following line and spacing dimensions (fibronectin line width [µm]/spacing sizes [µm]) were u...
<p>When we command the rectangular YS domain to extend over time (by setting the length of the recta...
<p>In the simulation of A/H dynamics, with Y and S having high concentrations inside the rectangle (...
<p>(<b>a</b>) The first activator peak emerges at the growing tip. (<b>b</b>) forward migration of t...
<p>The spatial pattern of activator A (<i>top left</i>) and inhibitor H (<i>top right</i>) overlap, ...
<p>(<b>a</b>) initial condition of Y and S: we place the rectangular YS domain in the center, with h...
<p>(A) Initial concentrations of morphogen, Fj, and Ds as used in the model. The morphogen is most c...
In both domains, an increase in decay of either the activator (μA, top rows) or the inhibitor (μH, b...
In all domains, an increase in diffusion of either the activator (DA, top two rows) or the inhibitor...
<p>The substrate stiffness changes linearly in <i>x</i> direction from 1 kPa at <i>x</i> = 0 to 100 ...
<p>For different values of (<b>A</b>) T<sub>e</sub> and σ<sub>e</sub> or (<b>B</b>) T<sub>a</sub> an...
<p>It is assumed that there is a chemoattractant substance with concentration of 5×10<sup>−5</sup> M...
<p>NALM-6 cells transduced with control or TAPP2 KD lentivirus were loaded onto a microfluidic chemo...
<p>F-actin protrusions produced by the two Leading Cells (LCs) on one side during epidermal cell mig...
Actin-based cell motility and force generation are central to immune response, tissue development, a...
<p>The following line and spacing dimensions (fibronectin line width [µm]/spacing sizes [µm]) were u...
<p>When we command the rectangular YS domain to extend over time (by setting the length of the recta...
<p>In the simulation of A/H dynamics, with Y and S having high concentrations inside the rectangle (...
<p>(<b>a</b>) The first activator peak emerges at the growing tip. (<b>b</b>) forward migration of t...
<p>The spatial pattern of activator A (<i>top left</i>) and inhibitor H (<i>top right</i>) overlap, ...
<p>(<b>a</b>) initial condition of Y and S: we place the rectangular YS domain in the center, with h...
<p>(A) Initial concentrations of morphogen, Fj, and Ds as used in the model. The morphogen is most c...
In both domains, an increase in decay of either the activator (μA, top rows) or the inhibitor (μH, b...
In all domains, an increase in diffusion of either the activator (DA, top two rows) or the inhibitor...
<p>The substrate stiffness changes linearly in <i>x</i> direction from 1 kPa at <i>x</i> = 0 to 100 ...
<p>For different values of (<b>A</b>) T<sub>e</sub> and σ<sub>e</sub> or (<b>B</b>) T<sub>a</sub> an...
<p>It is assumed that there is a chemoattractant substance with concentration of 5×10<sup>−5</sup> M...
<p>NALM-6 cells transduced with control or TAPP2 KD lentivirus were loaded onto a microfluidic chemo...
<p>F-actin protrusions produced by the two Leading Cells (LCs) on one side during epidermal cell mig...
Actin-based cell motility and force generation are central to immune response, tissue development, a...
<p>The following line and spacing dimensions (fibronectin line width [µm]/spacing sizes [µm]) were u...