<p>(A–B) Complex relationships between lineage complexity and robustness to (A) necrosis or (B) program failure among three types of random lineages. Each dot represents a random lineage, whereas the triangle shows the real lineage of <i>C. elegans</i>. <i>P</i><sub>1</sub> is the probability that the complexity is equal between the dots of two colors compared (Mann-Whitney <i>U</i> test), whereas <i>P</i><sub>2</sub> is the probability that the robustness (<i>f</i><sub>n</sub> or <i>f</i><sub>p</sub>) is equal between the dots of two colors compared (Mann-Whitney <i>U</i> test). All <i>P</i> values are calculated based on 10,000 dots of each color. For clarity, however, only 100 dots of each color are shown here. (C–D) Lineage complexity a...
Research in evolutionary biology is driven by curiosity about the evolution of complex organisms. Th...
<p>The effective size (<i>N<sub>e</sub></i>) of the populations evolved is given in the top row of t...
<p>A) Each row represents an independent evolution experiment and is named according to [<a href="ht...
<p>(A–E) Frequency distributions of (A) lineage robustness in the presence of necrosis (<i>f</i><sub...
<p>(A–B) Frequency distribution of the robustness of 10,000 random lineages (grey bars) in the prese...
<p>(A–B) Lineage robustness in the presence of (A) necrosis or (B) program failure declines with the...
<p>(A) A hypothetical cell lineage. Internal cells are prefixed with “I” and terminal cells are pref...
<p>(A) Frequency distribution of the maximum cell depth in 10,000 lineages (grey bars), which are ge...
<p>(A) Positive correlation between the depth of a terminal cell and its cell type size. Spearman's ...
<p>The horizontal axis shows the number of genes per network. Black bars on the vertical axis show t...
International audienceSystems biology is often viewed as reverse engineering of biological systems. ...
The rate and fitness effects of new mutations have been investigated by mutation accumulation (MA) e...
<p>(A) Change in robustness, measured as the difference of the mean phenotypic distances between unp...
BackgroundOrganisms use a variety of mechanisms to protect themselves against perturbations. For exa...
A major aim of evolutionary biology is to explain the respective roles of adaptive versus non-adapti...
Research in evolutionary biology is driven by curiosity about the evolution of complex organisms. Th...
<p>The effective size (<i>N<sub>e</sub></i>) of the populations evolved is given in the top row of t...
<p>A) Each row represents an independent evolution experiment and is named according to [<a href="ht...
<p>(A–E) Frequency distributions of (A) lineage robustness in the presence of necrosis (<i>f</i><sub...
<p>(A–B) Frequency distribution of the robustness of 10,000 random lineages (grey bars) in the prese...
<p>(A–B) Lineage robustness in the presence of (A) necrosis or (B) program failure declines with the...
<p>(A) A hypothetical cell lineage. Internal cells are prefixed with “I” and terminal cells are pref...
<p>(A) Frequency distribution of the maximum cell depth in 10,000 lineages (grey bars), which are ge...
<p>(A) Positive correlation between the depth of a terminal cell and its cell type size. Spearman's ...
<p>The horizontal axis shows the number of genes per network. Black bars on the vertical axis show t...
International audienceSystems biology is often viewed as reverse engineering of biological systems. ...
The rate and fitness effects of new mutations have been investigated by mutation accumulation (MA) e...
<p>(A) Change in robustness, measured as the difference of the mean phenotypic distances between unp...
BackgroundOrganisms use a variety of mechanisms to protect themselves against perturbations. For exa...
A major aim of evolutionary biology is to explain the respective roles of adaptive versus non-adapti...
Research in evolutionary biology is driven by curiosity about the evolution of complex organisms. Th...
<p>The effective size (<i>N<sub>e</sub></i>) of the populations evolved is given in the top row of t...
<p>A) Each row represents an independent evolution experiment and is named according to [<a href="ht...