Stable Steady State Analysis of Network 1.

<p>(A) A matrix defined by examining the number of SSS present at points where all auto-regulatory strengths (row) are equal and mutual-regulatory strengths (column) are also equal. This provides an overview of network stability at various points in the parameter regulation space; the green and brown regions are visualized as FCT diagrams independently in B. (B) The green-boxed diagram corresponds to the green-boxed parameter combination regime from (A), where genes have regulatory strengths α = 1 and β = 0.1. The orange-boxed diagram corresponds to the orange-boxed parameter combination regime from (A), where nodes have regulatory strengths α = 5 and β = 0.1. This parameter combination regime allows the system stability in 5 of the 8 Stable Steady States, losing only the two-ON states. (C) As in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0102873#pone-0102873-g004" target="_blank">Figure 4C</a>, there exist parameter combinations not captured by the matrix representation, where increased strength of any one of the five regulations (represented by thick arrows) will enable 5 SSS.