Overview of integrated network of genes regulated by both lncRNAs and miRNAs, that are crucial for precise neuronal development.

<p>Upregulated mRNAs/lncRNAs/miRNAs are shown in red font. Green font represents downregulated mRNAs/lncRNAs/miRNAs. LncRNAs associated with the gene are underlined. Black solid feedback arrows (→) on the gene indicate lncRNAs associated with the gene with synergistic expression. Black inhibitory arrows (⊥) indicate lncRNAs associated with the gene with reciprocal expression. Ten differentially expressed miRNAs targeting the respective genes are indicated. Solid lines (–) emerging from the miRNAs indicate validated targets. Dashed lines (----) indicate predicted targets as determined by TargetScan and microRNA.org. miRNAs shaded in grey (miR-329, -377, -495) belong to the miR-379-410 cluster.