<p>The <i>myc</i>-tag on the receptor and the locations of mutations used in the study are shown on the secondary structure model of MAS receptor. The transmembrane helices (TM) I - VII are predicted by bioinformatics analysis. Also shown in the model are the predicted ligand binding residues that were mutated in this study.</p
The precise nature of redox modulation of N-methyl-d-aspartate (NMDA) receptors is still unclear, al...
This work investigates the mechanisms of binding of T cell receptors (TCRs) to Class I MHC-peptide c...
International audienceThe thyrotropin receptor (TSHR) is a G protein-coupled receptor (GPCR) that is...
BACKGROUND: Mutations in the thrombopoietin receptor (MPL) may activate relevant pathways and lead t...
International audienceInternal motions and dynamics of macromolecules are essential to understand th...
International audienceThe snake toxin MT7 is a potent and specific allosteric modulator of the human...
The thyrotropin receptor (TSHR) is a G protein-coupled receptor (GPCR) that is member of the leucine...
A modelling study has been carried out, investigating the binding of histamine (Hist), 2-methylhista...
<p>Based on an analysis of the current atomic model, we analyzed interactions between residues (midd...
International audienceThe fundamental oncology-related research is required for a deeper understandi...
Item does not contain fulltextOBJECTIVE AND DESIGN: Investigation of the principles of ligand-recept...
The type III receptor tyrosine kinase (RTK) KIT plays a crucial role in the transmission of cellular...
<p><b>A</b>, Model structure of mOSM (amino acids 25–205 of NP_001013383.1, orange) and rOSM (amino ...
Next-generation sequencing methods have not only allowed an understanding of genome sequence variati...
The goal of this thesis project was the validation of our model of the mu opioid receptor, a member ...
The precise nature of redox modulation of N-methyl-d-aspartate (NMDA) receptors is still unclear, al...
This work investigates the mechanisms of binding of T cell receptors (TCRs) to Class I MHC-peptide c...
International audienceThe thyrotropin receptor (TSHR) is a G protein-coupled receptor (GPCR) that is...
BACKGROUND: Mutations in the thrombopoietin receptor (MPL) may activate relevant pathways and lead t...
International audienceInternal motions and dynamics of macromolecules are essential to understand th...
International audienceThe snake toxin MT7 is a potent and specific allosteric modulator of the human...
The thyrotropin receptor (TSHR) is a G protein-coupled receptor (GPCR) that is member of the leucine...
A modelling study has been carried out, investigating the binding of histamine (Hist), 2-methylhista...
<p>Based on an analysis of the current atomic model, we analyzed interactions between residues (midd...
International audienceThe fundamental oncology-related research is required for a deeper understandi...
Item does not contain fulltextOBJECTIVE AND DESIGN: Investigation of the principles of ligand-recept...
The type III receptor tyrosine kinase (RTK) KIT plays a crucial role in the transmission of cellular...
<p><b>A</b>, Model structure of mOSM (amino acids 25–205 of NP_001013383.1, orange) and rOSM (amino ...
Next-generation sequencing methods have not only allowed an understanding of genome sequence variati...
The goal of this thesis project was the validation of our model of the mu opioid receptor, a member ...
The precise nature of redox modulation of N-methyl-d-aspartate (NMDA) receptors is still unclear, al...
This work investigates the mechanisms of binding of T cell receptors (TCRs) to Class I MHC-peptide c...
International audienceThe thyrotropin receptor (TSHR) is a G protein-coupled receptor (GPCR) that is...