Silencing of HIF-1β affects expression of tumor growth-related genes.
- Sung Hoon Choi (605545)
- Ae Ri Chung (605546)
- Wonseok Kang (139862)
- Jun Yong Park (131968)
- Mi Sol Lee (605547)
- Shin Won Hwang (605548)
- Do Young Kim (131974)
- Seung Up Kim (131988)
- Sang Hoon Ahn (131984)
- Seungtaek Kim (89665)
- Kwang-Hyub Han (131978)
Publication date
July 2014
DOIAbstract
<p>Under hypoxic conditions, silencing of HIF-1β was associated with diminished expression of several genes related to tumor growth, such as EGF and HGF, but not FGF2. NT, non-target; siGFP, siRNA against green fluorescent protein; siHIF1-α, siRNA against HIF-1α; siHIF-1β, siRNA against HIF-1β; EGF, epidermal growth factor; HGF, hepatocyte growth factor; FGF2, fibroblast growth factor 2. *, <i>P</i><0.05.</p
Add to ORKG