Dynamic MHCII presentation and delayed activation of MΦs during co-infection.

<p>Spleen mononuclear cells were extracted on consecutive days from single and co-infected mice. They were stained and counted in a LCRII flow cytometer (N = 6 per group) experiment performed in duplicate. (A) The percentage fraction of MHCII expressing cells in the F4/80+ population of SMCs. (B) The proportion of F4/80+MHCII+ MΦs expressing MHCII to a high extent (MHCII+^high). (C) The fraction of CD11c+ DCs expressing the activation marker CD86. (D) The fraction of F4/80+MHCII+^low cells expressing CD86. (E) The fraction of F4/80+MHCII+^high cells expressing CD86, (▪) indicates mice infected with both <i>P. berghei</i> and <i>B. duttonii</i>, (○) <i>B. duttonii</i> infected animals, and (Δ) mice infected with <i>P. berghei</i>.