Metabolic changes following treatment of KNS42 pediatric glioblastoma cells with PI-103.
- Nada M. S. Al-Saffar (454143)
- Lynley V. Marshall (607343)
- L. Elizabeth Jackson (607344)
- Geetha Balarajah (607345)
- Thomas R. Eykyn (454146)
- Alice Agliano (607346)
- Paul A. Clarke (607347)
- Chris Jones (25458)
- Paul Workman (54973)
- Andrew D. J. Pearson (373289)
- Martin O. Leach (454145)
Publication date
August 2014
DOIAbstract
<p>Representative <i>in vitro</i> (A) <sup>31</sup>P-NMR spectra and (B) expansion of <sup>1</sup>H-NMR spectra regions representing choline–containing metabolites (left) or lactate (Lac; right) of KNS42 aqueous cell extracts following 12 or 24 hours treatment with PI-103 (5×GI<sub>50</sub>) compared to vehicle (DMSO) treated control.</p
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