<p><sup>1</sup>Only data that accrued until the study participant was prematurely withdrawn from the study were included in the modified intention-to-treat analysis. <sup>2</sup>Complete data included in the modified intention-to-treat analysis.</p
<p>Of 242 screened volunteers, 120 subjects were assessed eligible for enrollment, allocated to one ...
<p>Study was terminated before the expansion part of phase IIb. *One patient was randomized to the l...
Missing outcome data are common in clinical trials and despite a well-designed study protocol, some ...
<p>incomplete FU, incomplete follow-up (i.e., the study was terminated before the participant comple...
<p>“Withdrawn” indicates participants’ withdrawal from trial and all associated research activities....
<div><p>This figure describes the state of the trial corresponding to planned visits up to 30 April ...
<p> † It is possible that the investigators collected but did not report the data. * Data analysis m...
<p>* The patient who was lost to follow-up at 3 months was excluded from the analysis of the 3 month...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/112012/1/sim6352.pd
Treatment effects are often evaluated by comparing change over time in outcome measures. However, va...
<p>I<sub>X</sub> indicates timing of assessments. One participant withdrew from the study during sta...
to treat analysis in clinical trials when there are missing data The problem If you open any book ab...
Clinical studies mostly generate incomplete data. The fraction of non-available data can range from ...
<p>*Participants who had withdrawn, were lost to follow-up or had died were not invited.</p
a<p>Number of participants included in the intent-to-treat or modified intent-to-treat analysis on t...
<p>Of 242 screened volunteers, 120 subjects were assessed eligible for enrollment, allocated to one ...
<p>Study was terminated before the expansion part of phase IIb. *One patient was randomized to the l...
Missing outcome data are common in clinical trials and despite a well-designed study protocol, some ...
<p>incomplete FU, incomplete follow-up (i.e., the study was terminated before the participant comple...
<p>“Withdrawn” indicates participants’ withdrawal from trial and all associated research activities....
<div><p>This figure describes the state of the trial corresponding to planned visits up to 30 April ...
<p> † It is possible that the investigators collected but did not report the data. * Data analysis m...
<p>* The patient who was lost to follow-up at 3 months was excluded from the analysis of the 3 month...
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/112012/1/sim6352.pd
Treatment effects are often evaluated by comparing change over time in outcome measures. However, va...
<p>I<sub>X</sub> indicates timing of assessments. One participant withdrew from the study during sta...
to treat analysis in clinical trials when there are missing data The problem If you open any book ab...
Clinical studies mostly generate incomplete data. The fraction of non-available data can range from ...
<p>*Participants who had withdrawn, were lost to follow-up or had died were not invited.</p
a<p>Number of participants included in the intent-to-treat or modified intent-to-treat analysis on t...
<p>Of 242 screened volunteers, 120 subjects were assessed eligible for enrollment, allocated to one ...
<p>Study was terminated before the expansion part of phase IIb. *One patient was randomized to the l...
Missing outcome data are common in clinical trials and despite a well-designed study protocol, some ...