Effects of sub-acute DM199 dosing and drug wash-out.

<p>11-week old male ZDF rats (n = 8) were fasted overnight (12 hrs.) and injected s.c. with either PBS (Control) or DM199 (25, 100 or 400 µg/kg) on days 1, 4 and 7 (arrows), with no subsequent treatments for a 7 day period. Fasting blood glucose levels were measured daily just prior to treatment. *<i>p<</i>0.05; **<i>p<</i>0.01 with respect to control treatment.