PCA analysis of the averaged MS spectra of phosopholipids from liver tissue sections obtained from 3 different conditions in positive ionization mode and comparison of MALDI images of phospholipids in regenerating liver tissues after partial hepatectomy.

<p>(A) Typical MS spectra of liver tissue sections in 3 different conditions obtained from imaging mass spectrometry. (B) PCA analysis of the IMS data acquired in positive-ionization mode. (C, D) Representative MALDI images of molecular ions showing alterations in their levels according to HBV infection with or without HBx expression. (E) H&E-stained liver tissues 24 h after partial hepatectomy. h after partial hepatectomy.