HRV-induced permeability is size-selective.

<p>Liposomes containing FITC-labelled dextrans of 4 kD (FD4), 10 kD (FD10), 70 kD (FD70) or 250 kD (FD250) were mixed with 0.5 µg HRV or preheated HRV. Release of dextrans was quantified by pelleting the liposomes and measuring the fluorescence in the supernatant (as in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1004294#ppat-1004294-g004" target="_blank">figure 4</a>). Data is presented as percentage of total release observed by lysis of liposomes by addition of detergent. Error bars represent standard error of the mean (n = 3) and asterisks indicate statistical significance calculated by one way Anova (p*<0.05). Data is representative of three independent experiments.