The Role of Cell Cycle Effects.

<p>(A) Method for determining cell growth rate. Measurements are taken at 2 time points, the first frame and final frame. The final frame is determined by the event. For an uninfected cell (grey) this is the point at which the cell divides. For an infected cell it is the point at which a decision of lysis (green) or lysogeny (red) has been made. The growth rate was calculated using where is the time between the first frame and the final frame. (B) Observed growth rates at different MOI. (C) Effect of cell growth on rate of lysogeny by considering dilution only. Fast rate and slow rate . (D) Effect of growth rate on rate of lysogeny when also considering possible changes in transcription rates. Growth rate modulation of transcription rate are similar to the study by Klumpp <i>et al. </i><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0103636#pone.0103636-Klumpp1" target="_blank">[33]</a>, with a two fold enhancement in the slower transcription rate case.